Research & Education

Active Trials

Working with researchers at Baylor Scott & White Health and institutions around the globe, our physicians, surgeons and advanced practice providers oversee a wide selection of clinical trials.

Filter:

Study Name: GEMINI

Indication: Hypertension
PI: East, Cara
Therapeutic Group: Cardiology – General

Study Name: RAPID

Indication: Thoracic aortic aneurysm (TAA)
PI: Brinkman, William T.
Therapeutic Group: Cardiovascular Surgery

Study Name: MonarQ EFS

Study Title: A Clinical Study of the inQB8 MonarQ Transcatheter Tricuspid Valve Replacement System 
Indication: Tricuspid regurgitation (TR)
PI: Smith II, Robert L.
Therapeutic Group: Tricuspid

Study Name: OCEAN(a)-PreEvent

Study Title: A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing Olpasiran Use to Prevent First Major Cardiovascular Events in Participants with Elevated Lipoprotein(a)
PI: East, Cara
Therapeutic Group: Cardiology – General

Study Name: FORTITUDE HCM

Study Title: A Global Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients with Symptomatic Non obstructive Hypertrophic Cardiomyopathy
PI: Afzal, Aasim
Therapeutic Group: Heart Failure

Study Name: TiGER

Study Title: A Global Post Market Evaluation of Terumo Aortic Endovascular Grafts
Indication: Thoracic aortic aneurysm (TAA)
PI: Gable, Dennis R.
Therapeutic Group: Vascular

Study Name: PLAQUE

Study Title: A multi-center, randomized, double-blind, placebo-controlled, parallel -group Phase IIIb study evaluating the effect of inclisirin on atherosclerotic plaque progression assessed by coronary computed tomography angiography (CCTA) in participants with a diagnosis of non-obstructive coronary artery disease without previous cardiovascular events
Indication: Atherosclerotic CV disease
PI: East, Cara
Therapeutic Group: Cardiology – General

Study Name: PolyACS

Study Title: A Polypill Strategy for the Treatment of Patients After Acute Coronary Syndrome – A Multicenter, Randomized, Controlled Trial
PI: Banerjee, Subhash; Keshvani, Neil
Therapeutic Group: Cardiology – Coronary

Study Name: SELUTION 4 DE NOVO

Study Title: A Prospective Randomized Single-Blind Multicenter Study to Assess the Safety and Effectiveness of the SELUTION SLR 014 PTCA Drug Eluting Balloon in the Treatment of Subjects with De Novo Coronary Lesions in Small Vessels
PI: Stoler, Robert C.; Widmer, Robert; Sayfo, Sameh
Therapeutic Group: Cardiology – Coronary

Study Name: PROACTIVE-HF-2

Study Title: A Prospective, Multi-Center, Open Label, Randomized Control Clinical Trial Evaluating the Safety and Efficacy of the Cordella™ Pulmonary Artery Sensor System in New York Heart Association (NYHA) Class II-III Heart Failure Patients
Indication: Acute decompensated
PI: Guerrero, Cesar Y.
Therapeutic Group: Heart Failure

Study Name: BOLT

Study Title: A Prospective, Multicenter Study of Patients with Deep Vein Thrombosis to Evaluate the Safety and Efficacy of the Indigo Aspiration System
Indication: DVT
PI: Vasquez, Javier Jr.
Therapeutic Group: Vascular

Study Name: Fenestrated TREO IDE

Study Title: A prospective, multicenter, non-blinded pivotal study of the Fenestrated TREO Stent-Graft system in subjects with the Abdominal Aortic Aneurysms (AAA) Requiring a Fenestrated Graft and Suitable for Endovascular Repair
PI: Vasquez, Javier Jr.
Therapeutic Group: Vascular

Study Name: Partner 3

Study Title: A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients Requiring Aortic Valve Replacement who have Severe, Calcific, Symptomatic Aortic Stenosis – PARTNER 3 Low-Risk Continued Access
Indication: Aortic stenosis (AS)
PI: Szerlip, Molly I.; Mack, Michael J.
Therapeutic Group: Aortic Valve

Study Name: PREVAIL GLOBAL

Study Title: A randomized controlled study of the Prevail Drug-Coated Balloon in subjects with in-stent restenosis and a single arm prospectively enrolled study of the Prevail Drug-Coated Balloon for de novo lesions in small vessel disease (Prevail Global)
Indication: In-stent restenosis (ISR)
PI: Stoler, Robert C.
Therapeutic Group: Cardiology – Coronary

Study Name: Engulf

Study Title: A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism (ENGULF)
Indication: Pulmonary embolism
PI: Dib, Chadi
Therapeutic Group: Cardiology – Peripheral

Study Name: ARTIST AR

Study Title: A Study to Assess Safety and Effectiveness of the JenaValve Trilogy™ Transcatheter Heart Valve System Versus Surgical Valve Replacement in Patients with Aortic Regurgitation
PI: Potluri, Srinivasa P.; Stoler, Robert C.
Therapeutic Group: Aortic Valve

Study Name: AAA-Shape

Study Title: AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion
Indication: Abdominal aortic aneurysm (AAA)
PI: Kedora, John C.; Vasquez, Javier Jr.
Therapeutic Group: Vascular

Study Name: VT PAS

Study Title: Abbott Ventricular Tachycardia Post Approval Study
Indication: Ventricular tachycardia
PI: Rao, Praveen
Therapeutic Group: Electrophysiology

Study Name: eVO2

Study Title: An Observational, Non-Interventional Study Supporting Validation of VO2Max estimation Methods using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)
Indication: VO2Max validation
PI: Afzal, Aasim
Therapeutic Group: Heart Failure

Study Name: CRT – Nitro

Study Title: Analysis of Coronary Reactivity Testing With And Without Intracoronary Nitrate Testing
PI: Widmer, Robert
Therapeutic Group: Cardiology – Coronary

Study Name: BIOFLOW VII

Study Title: BIOTRONIK – A Prospective Multicenter Study to Confirm the SaFety and Effectiveness of the Orsiro SiroLimus Eluting Coronary Stent System in the Treatment Of Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions – VI
Indication: CAD (General)
PI: Stoler, Robert C.
Therapeutic Group: Cardiology – Coronary

Study Name: CSWG

Study Title: Cardiogenic Shock Working Group Registry
Indication: Cardiogenic shock
PI: Afzal, Aasim
Therapeutic Group: Heart Failure

Study Name: CLEAR-VIEW XT

Study Title: Cleaner Long-tErm Assessment Registry – Venous Insights and Efficacy With eXtended Tracking
Indication: DVT
PI: Foteh, Mazin I.
Therapeutic Group: Cardiology – Peripheral

Study Name: LYTEN

Study Title: Comparison of the Balloon-Expandable Edwards Valve and Self-Expandable Evolut (R/PRO) System for the Treatment of Small, Severely Dysfunctional Surgical Aortic Bioprostheses: A Pilot Prospective Randomized Trial.
Indication: Aortic valve in valve (AViV)
PI: Al-Azizi, Karim M.
Therapeutic Group: Aortic Valve

Study Name: Calyan Pacemaker EFS

Study Title: Early feasibility evaluation of a novel pacemaker system
PI: Yousif, Ali
Therapeutic Group: Electrophysiology

Study Name: RESTOR BTK

Study Title: Early Feasibility Study for Peripheral-5 CTO Crossing System (PER-5) in Below-The-Knee (BTK) Arteries
Indication: PAD – CTO
PI: Sayfo, Sameh
Therapeutic Group: Cardiology – Peripheral

Study Name: RESTOR-COR-1

Study Title: Early Feasibility Study of the AngioSafe Coronary CTO Crossing System
PI: Potluri, Srinivasa P.
Therapeutic Group: Cardiology – Coronary

Study Name: CardioMech EFS

Study Title: Early Feasibility Study of the CardioMech Mitral Valve Repair System (MVRS)
PI: Al-Azizi, Karim M.; Smith II, Robert L.
Therapeutic Group: Mitral Valve

Study Name: Arise III

Study Title: Evaluation of the GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections
PI: Brinkman, William T.
Therapeutic Group: Cardiovascular Surgery

Study Name: Pivotal TBE (Gore)

Study Title: Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (SSB 11-02)
Indication: Thoracic aortic aneurysm (TAA)
PI: Brinkman, William T.
Therapeutic Group: Vascular

Study Name: Portico NG

Study Title: Evaluation of the Portico™ NG (Next Generation) Transcatheter Aortic Valve in High and Extreme Risk Patients With Symptomatic Severe Aortic Stenosis
Indication: Aortic stenosis (AS)
PI: Harrington, Katherine B.
Therapeutic Group: Aortic Valve

Study Name: FASTR II

Study Title: Fluid management of Acute decompensated heart failure Subjects Treated with Reprieve System – FASTR II Trial
PI: Gottlieb, Robert L.
Therapeutic Group: Heart Failure

Study Name: SPYRAL ON

Study Title: Global Clinical Study of Renal Denervation with the Symplicity Spyral multi-electrode renal denervation system in Patients with uncontrolled Hypertentsion on Standard Medical Therapy.
Indication: Hypertension
PI: Choi, James W.
Therapeutic Group: Cardiology – General

Study Name: LOQI Registry

Study Title: Long-Term Outcome and Quality Indicator (LOQI) Impella Registry
Indication: Impella registry
PI: Afzal, Aasim
Therapeutic Group: Heart Failure

Study Name: LumiGuide

Study Title: LumiGuide Xperience Registry
Indication: Abdominal aortic aneurysm (AAA)
PI: Foteh, Mazin I
Therapeutic Group: Vascular

Study Name: OPTIMAL (miRNA)

Study Title: OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
Indication: Heart transplant
PI: Hall, Shelley A.
Therapeutic Group: Heart Failure

Study Name: DEFINE GPS

Study Title: Philips Image Guided Therapy Devices/ “Distal Evaluation of Functional performance with Intravascular sensors to assess the Narrowing Effect: Guided Physiologic Stenting” (DEFINE GPS)
Indication: CAD (General)
PI: Al-Azizi, Karim M.
Therapeutic Group: Cardiology – Coronary

Study Name: Support II

Study Title: Pivotal Randomized Study of the SUpira System in Patients Undergoing High-Risk Percutaneous CoroNary Intervention (HRPCI) The SUPPORT II Trial
PI: Al-Azizi, Karim M.
Therapeutic Group: Cardiology – Coronary

Study Name: Disrupt PAD BTK II (BTK)

Study Title: Prospective, Multi-center, Single-arm Study of the Shockwave Medical Peripheral Intravascular Lithotripsy (IVL) System for Treatment of Calcified Peripheral Arterial Disease (PAD) in Below-the-Knee (BTK) Arteries (Disrupt PAD BTK II)
Indication: PAD – BTK
PI: Sayfo, Sameh
Therapeutic Group: Cardiology – Peripheral

Study Name: Forward CAD

Study Title: Prospective, Multicenter, Single-Arm, Investigational Device Exemption (IDE) Study of the Shockwave Intravascular Lithotripsy (IVL) System with the Shockwave Javelin Coronary IVL Catheter (FORWARD CAD IDE Study)
Indication: CAD – CTO
PI: Potluri, Srinivasa P.
Therapeutic Group: Cardiology – Coronary

Explore our research initiatives

Driving the field of cardiovascular care forward

Previous

Next